Multiple Choice
Identify the letter of the choice that
best completes the statement or answers the question.
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1.
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Viral
taxonomy is not based upon: a. | type of nucleic acid | b. | type of capsid | c. | enveloped or nonenveloped | d. | type of host | e. | fever of unknown origin | | |
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2.
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The
factor that determines whether a virus binds and enters a cell is molecular recognition of viral and
cellular __ receptors. Cells of different __ bear surface receptors that range from very
specific to universal. Thus a given virus attaches a few to many, depending upon receptor
__. a. | core, origin,
number | b. | surface, tissues,
specificity | | | | |
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3.
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In
general, most __ viruses depart their host cell by budding from the nucleus; while most __ viruses
bud from the cytoplasmic membrane.
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4.
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Childhood viral infections such as these, range from inconsequential to lethal, and
are usually transmitted via aerosol droplets, and direct contact. On the other hand, __ is a
zoonotic virus transmitted by a vector. a. | measles | b. | viral encephalitis | c. | rubella | d. | mumps | e. | chickenpox | | |
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5.
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Viral
infections may be local or disseminate. Typical of primary infections remaining at the portal
of entry is __ , and of those becoming viremic and systemic is __. a. | influenza, mumps | b. | polio, colds | | | | |
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6.
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Viral
infection may be: a. | mild,
asymptomatic | b. | self-limited,
unavoidable | c. | strictly human or
zoonotic | d. | severe,
deadly | e. | all of
these | | |
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7.
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Pathogenic DNA viruses are grouped according to types of: a. | double strandedness | b. | target cells | c. | single strandedness | d. | envelope possession | e. | all of these | | |
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8.
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The
poxviruses, herpesviruses, and hepadnaviruses are __ DNA viruses. The adenoviruses,
papovaviruses, and parvoviruses are __ DNA viruses. a. | nonenveloped, enveloped | b. | enveloped, nonenveloped | | | | |
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9.
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The
etiologic agent of smallpox is __ virus.
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10.
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Unlike
similar efforts to control other pathogens, smallpox eradication by vaccination was "easy"
because variola: a. | is genetically
stable | b. | is not
latent | c. | is not harbored
by carriers | d. | is not prone to
mutate | e. | all of
these | | |
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11.
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Variola is an potential weapon, but not because: a. | it is virulent and contagious | b. | of population nonimmunity | c. | inhalant, contact exposure | d. | it is air dispersable | e. | it is a poxvirus | | |
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12.
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The
agent responsible for __ is a herpes virus, and is not a pox virus at all. a. | buffalopox | b. | rabbitpox | c. | elephantpox | d. | chickenpox | e. | mousepox | | |
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13.
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The
natural animal reservoir of chickenpox virus is: a. | humans | b. | poultry | c. | dairy cows | d. | monkeys | e. | all of these | | |
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14.
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Humans
appear to be the natural reservoir of two herpes simplex viruses. HSV-1 is responsible for __
lesions, and HSV-2 causes lesions of the __. Ordinary enviromental conditions are too harsh for
herpesvirus, thus direct, mucosal exposure to infectious secretions is usually involved in
transmission. a. | genitalia,
ororpharyngeal | b. | oropharyngeal,
genitalia | | | | |
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15.
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HSV-1
is the agent for self-limiting __ or fever blisters, of the oral cavity. In susceptible
children, herpetic __, a severe ulceration of the oral mucosa, occurs. It may be complicated by
sore throat, swallowing difficulty and other symptoms. a. | cold sores,
gingivostomatitis | b. | keratitis, herpes
labialis | | | | |
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16.
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The
occurance of HSV-2 genital herpes coincides with __ maturation and activity. The eruption of __
in and around the genitalia is accompanied by distressing symptoms. Infection is self-limiting
but recurrent bouts may occur, often in response to __ stress, menstruation, and concurrent
infection, although symptoms are less severe. a. | psychological, hair,
growing | b. | sexual, vesicles,
traumatic | | | | |
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17.
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Unlike
adult infection, __ herpes is much more severe and potentially life-threatening. Infection
occurs in transit via __ delivery. Infant mortality is about 30% if only the eyes, mouth, and
skin are involved but rises to 80% with __ complications. a. | neonatal, natural, CNS | b. | fetal, cesarean, umbilical | | | | |
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18.
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To
avert neonatal herpes, the need to carry out cesarian section is most urgent in a near term mother
with history of recurrent __ infection. a. | herpetic keratitis | b. | herpetic whitlow | c. | cold sores | d. | herpes labialis | e. | genital herpes | | |
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19.
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Acyclovir is presently the most effective treatment for herpes simplex. A daily
oral dose for 6-12 months helps prevent __ genital herpes. Topical medications reduce the
duration of infection and viral shedding. Nonprescription coldsore medications are soothing but are
not directly __. a. | latent,
antibiotic | b. | recurrent,
antiviral | | | | |
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20.
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The
varicella-zoster virus (VSV) is responsible for __ (chickenpox) and its recurrent sequela, herpes __
(shingles). a. | varicella,
zoster | b. | shingles,
chickenpox | c. | chickenpox,
varicella | d. | zoster,
varicella | e. | zoster,
shingles | | |
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21.
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In
most cases of chickenpox, recovery confers __ immunity against reinfection. Even subclinical
infection can confer __ protection. a. | lasting, enduring | b. | childhood, adulthood | | | | |
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22.
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Some
parents regard chickenpox as an inevitable road to developing childhood immunity and deliberately
permit exposure to overt cases. Perhaps this practice would have merit were it not for the
prospect of __ and the development of __. a. | zoster, delayed allergy | b. | latency, shingles | | | | |
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23.
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Consequences of fetal or neonatal CMV infection excludes: a. | normal birth | b. | capillary bleeding, retardation | c. | impaired hearing, visual defects | d. | liver, spleen enlargement | e. | microencephaly, ocular
inflammation | | |
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24.
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The
etiologic herpesvirus of roseola infantum, an acute febrile disease of babies is: a. | T-lymphotrophic virus 6 | b. | Epstein-Barr virus | c. | herpes simplex virus 1 | d. | herpes simplex virus 2 | e. | varicella-zoster virus | | |
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25.
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Of the
major hepatitis viruses, __ is the only DNA virus that causes hepatitis. a. | HAV | b. | HBV | c. | HCV | d. | HDV delta agent | e. | HEV | | |
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26.
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Hepatitis D virus, also called __ agent, is a defective RNA virus that is benign
unless the same cell is coinfected with __.
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Matching
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Matching, DNA viruses and diseases:
a. | poxviridae | d. | adenoviridae | b. | herpesviridae | e. | papovaviridae | c. | hepadnaviridae | f. | parvoviridae | | | | |
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27.
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__
hepatitis B
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28.
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__
colds, keratoconjunctivitis
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29.
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__
cold sores, mononucleosis
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30.
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__
erythema infectiosum
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31.
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__
smallpox, molluscum contagiosum
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32.
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__
warts, leucoencephalopathy
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